What is Antimicrobial Resistance?

  • Antimicrobial Resistance refers to a phenomenon where microbes have developed resistances to certain antibiotics due to genetic adaptations. This can be done:
    • by resisting changes caused by drugs that can alter bacterial genetic information.
    • by developing enzymes that can break down the drugs into safer compounds.
    • by conjugation—passing drug resistances across organism species or by random mutations (which is more apparent for viruses.)
  • This arose due to the use of antibiotics in almost anything disease-related, thus causing microbes to develop appropriate adaptations.

Other Notes

  • Liposomes (and in particular stealth liposomes) are important in the research of drugs as they allow injection molecules into the plasma membrane.
  • Many drugs act by inhibiting the transport of transmitters out of the synaptic cleft.

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